Administrative Professional Day 2025. Administrative professionals day falls on april 24, 2025.  — administrative professionals day, otherwise known as national secretaries day, is held annually on the last wednesday of the last full week of april.

 — administrative professionals day, otherwise known as national secretaries day, is held annually on the last wednesday of the last full week of april.  — administrative professionals day 2025 is on wednesday, april 24, recognizing in the united states the contributions secretaries and administrative assistances make to our economy.